Description: The mouse IP-10 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of mouse IP-10. The mouse IP-10 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
IP-10 is a member of the CXC subfamily of chemokines expressed by monocytes. It plays a pivotal role in immune system development and deployment. The Interferon-gamma inducible protein -10kD (IP-10) displays pleiotropic functions including stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis.
Through this inhibitory effect on neovascularization IP-10 exhibits anti-tumoral effects. It shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 is further involved in allergic contact dermatitis reactions and other allergic diseases. It appears during immune-mediated processes, in inflammation of the nervous system and in Alzheimer's disease.
Its involvement in the regulation of fibroproliferation following inflammatory lung injury has been described.
Components
Aluminium pouch(es) with a Microwell Plate coated with polyclonal antibody to mouse IP-10
Biotin-Conjugate anti-mouse IP-10 polyclonal antibody
Streptavidin-HRP
Mouse IP-10 Standard lyophilized, 1000 pg/mL upon reconstitution
Sample Diluent
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films
京公网安备11010802025653 版权所有：北京逸优科技有限公司
