Description: The human anti-IFN-alpha ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human anti-IFN-alpha. The human anti-IFN-alpha ELISA is for research use only. Not for diagnostic or therapeutic procedures.
It is a common concept that the development of antibodies against any autoantigen or drug is always undesirable. Such antibodies are crucial for the pathology of autoimmune diseases and inhibit the pharmacological effects of drugs including exogenously administered cytokines.
Antibodies to IFN-alpha were detected in patients with various autoimmune disorders and in the serum of patients with systemic lupus erythematosus. Spontaneous antibodies to IFN-alpha were shown to occur in sera of various cancer patients. Neutralizing IFN-alpha antibodies were also found in cerebrospinal fluids and sera of acute aseptic meningitis patients as well as in patients with chronic polyarthritis.
The anti-IFN-alpha product is manufactured and sold in the United States under license from Pestka Biomedical Laboratories, Inc. (d/b/a PBL InterferonSource) solely for research use in the form in which it is originally manufactured, packaged and sold. Any modification, repackaging, or alteration of the product, and any use for diagnostic, therapeutic or clinical purposes is strictly prohibited.
Components
Aluminium pouch(es) with a Microwell Plate coated with recombinant human IFN-alpha
HRP-Conjugate human IFN-alpha protein
Human anti-IFN-alpha Standard, 200 ng/mL
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Adhesive Films
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