Description: The human TIMP-1 ELISA is an enzyme-linked immunosorbent assay for the quantitative detection of human tissue inhibitior of metallo-proteinase-1 (TIMP-1). The human TIMP-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
The tissue inhibitions of metalloproteinases (TIMPs) are naturally occurring proteins that specifically inhibit matrix metalloproteinases, thus maintaining balance between matrix destruction and formation. An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors.
TIMP-1 has been shown to inhibit tumor-induced angiogenesis. An imbalance of MMP/TIMP regulation has been implicated in several inflammatory diseases of the nervous system. In the pathogenesis of vascular diseases TIMP-1 seems to be down regulated.
Components
Aluminium pouch(es) with a Microwell Plate coated with monoclonal antibody to human TIMP-1
Biotin-Conjugate anti-human TIMP-1 polyclonal antibody
Streptavidin-HRP
Human TIMP-1 Standard lyophilized, 5 ng/ml upon reconstitution
Assay Buffer Concentrate 20x (PBS with 1% Tween 20 and 10% BSA)
Wash Buffer Concentrate 20x (PBS with 1% Tween 20)
Substrate Solution (tetramethyl-benzidine)
Stop Solution (1M Phosphoric acid)
Blue-Dye
Green-Dye
Red-Dye
Adhesive Films
京公网安备11010802025653 版权所有：北京逸优科技有限公司
