ATP Synthase Bta Pure 10 50ug

ATP synthase is a large enzyme complex that uses an electrochemical H+ or Na+ gradient to synthesize ATP from ADP and Pi, providing the

organism with the ATP needed for energy. The complex consists of two major units, F0 and F1. F0 is embedded in the inner membrane of the

mitochondria and, due to its hydrophobic nature, translocates protons across this membrane. F1 is the catalytic portion in the matrix region of

the mitochondria and is comprised of α, β, γ, δ, and ε subunits at a 3:3:1:1:1 ratio. The β subunit is synthesized in the nuclear

genome,transported to the mitochondria, and assembled with the other subunits. It is encoded by a single copy gene, is ubiquitously expressed

and highly conserved among species. ATP synthase β contains an Ets domain binding site, which is a main site for promoter activity. Ets

proteins contain domains that are involved in transcriptional activation, protein-protein interactions, and intramolecular repression of DNA

binding. This site acts as a target for transcriptional control by the Ets family of transcription factors. Thus, ATP synthase β is involved in the

synthesis of ATP and is controlled in part by ETS family proteins.

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.This antibody has been developed and certified for the bioimaging application. However, a routine bioimaging test is not performed on every lot. Researchers are encouraged to titrate the reagent for optimal performance.