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Ninjurin Pure 50/Ninjurin 150ug

  • 产品编号:BD-610777      品牌:BD-Pharmingen       原厂货号:610777
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 150ug
运保温度: Store undiluted at -20°C.
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描述:

Ninjurin is a protein whose expression is dramatically increased after sciatic nerve transection and crush injuries. The Ninjurin gene encodes
for a protein of 152 amino acids with two putative transmembrane domains. Ninjurin was iodinated in vivo and promoted the aggregation of
Jurkat cells expressing Ninjurin, indicating a portion of Ninjurin is exposed to the cell surface. The adhesive properties of Ninjurin were
energy and temperature dependent, required Ca2+ and Mg2+, and the integrity of the cytoskeleton. Also, the adhesion domain of Ninjurin is
located at the extracellular NH2-terminal domain. Although its predicted mass is 16 kDa, Ninjurin migrates as a 18-22 kDa protein in
SDS-PAGE, depending on the cell line or tissue. mRNA analysis revealed that Ninjurin is widely expressed with the highest levels in liver,
thymus, heart, and the lowest level in brain.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at -20°C.


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