RanBP1 Pure 35/RanBP1 50ug

产品编号：BD-610756 品牌：BD-Pharmingen 原厂货号：610756
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C.

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

Ran is a highly conserved GTPase that is ubiquitously expressed. Ran has been implicated in a number of cellular processes such as the
initiation of DNA replication, entry into and exit from mitosis, and in nuclear RNA and protein transport through the nuclear pore complex. A
number of Ran binding proteins have been identified. One of the smaller proteins identified is a 29kDa cytosolic molecule known as RanBP1.
The GTP-bound state of Ran is stabilized through its binding to RanBP1. In addition, RanBP1 appears to regulate the activity of Ran-GAP1
(Ran-GTPase activating protein) by increasing GTP hydrolysis. RanBP1 also inhibits the function of the guanine nucleotide exchange factor
RCC1 (regulator of chromosome condensation). Therefore, RanBP1 is responsible for the GTP-bound state of Ran and the increased GTP
hydrolysis of Ran GTP.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at -20°C.