Annexin VII Pure 5/Annexin VII 50ug

产品编号：BD-610668 品牌：BD-Pharmingen 原厂货号：610668
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C.

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描述：

Annexin VII, also known as synexin, is a member of the Annexin family characterized by Ca2+ dependent phospholipid binding. Annexins

have a four-fold internal repeat of about 70 amino acids that contains the Ca2+-binding sites. They also have a regulatory NH2-terminal region

of 30-40 amino acids. Annexin VII mRNA has been detected in many tissues and is most abundant in brain, heart, skeletal muscle, and lung.

Annexin VII mRNA exhibits a tissue dependent polymorphism due to alternative splicing which results in two different isoforms of 47 kDa

and 51 kDa. In vitro, Annexin VII aggregates chromaffin granules and enhances membrane fusion in a Ca2+ and GTP-dependent manner.

Although the physiological role of Annexin VII is not completely understood, it is believed to influence and regulate Ca2+ dependent events

such as secretion at the plasma membrane.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.