ROCK-II/ROK Alp Pure 21/ROCK-II 50ug

产品编号：BD-610623 品牌：BD-Pharmingen 原厂货号：610623
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C.

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描述：

Activity of the GTP-binding proteins is regulated by GAPs, that accelerate binding, and GTPases, that enhance the rate of GTP hydrolysis (Ras, Rho, cdc42Hs, and Rac). The isoforms of Rho, a small GTP-binding protein, regulate cellular processes such as the formation of the stress fibers, lamelipodia, and filopodia. ROKα (RhoA-binding kinase) is a Ser/Thr protein kinase that interects with the GTP-binding form of RhoA. Like RhoA, ROKα localizes at the cellular margins and colocalizes with acti filaments. The ROKα gene encodes a protein of 1302 amino acids with homology to the human myotonic kinase. Although ROKα binds to GTP-RhoA, it is not yet clear whether this interaction induces the kinase activity of ROKα.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at -20°C.