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Cdc37 Pure 15/Cdc37 50ug

  • 产品编号:BD-610576      品牌:BD-Pharmingen       原厂货号:610576
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装:
运保温度: Store undiluted at -20°C .
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描述:

Progression through the cell cycle is determined by numerous extracellular factors that convey their messages to the cyclin-dependent kinases
(cdk). Cdks are regulated by factors such as the availability of cyclins, inhibitors like Cip1 and Kip1, and phosphatases. CDC37 (50kDa), a
regulator of the cell cycle, targets Cdk4. CDC37 was identified in a complex with pp60v-src and Raf-1. In vitro assays revealed CDC37 as a

subunit of Hsp90 which associates with Cdk4. The overall result of this binding appears to be a shorter half-life of Cdk4.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at -20°C .


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