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Bta-Arrestin1Pure10/Bta-Arrestin1 150ug

  • 产品编号:BD-610551      品牌:BD-Pharmingen       原厂货号:610551
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 150ug
运保温度: Store undiluted at -20°C .
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描述:

β-Arrestins were discovered due to their ability to modulate interactions between the phosphorylated β2-Adrenergic receptors and G proteins.
This modulation results in diminished β2-Adrenergic receptor function, also known as desensitization. Because arrestins are found at the
synaptic terminals, they may provide a termination mechanism that allows the neurons to regain their original polarization and respond to a
new neurotransmitter stimulus. The C-terminal region of arrestins is involved in selecting the phosphorylated and activated adrenergic
receptors. The β-Arrestin1 gene encodes a protein of 418 amino acids with an approximate molecular weight of 55kDa. β-Arrestin1 protein is
highly homologous to the 45kDa β-Arrestin2. Both proteins are widely expressed, but are especially abundant in the central nervous system.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at -20°C .


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