With the exception of Hsp110, the stress or heat shock proteins have been thoroughly characterized. Hsp110 has been reported to be expressed
in most tissues. Like other stress proteins, Hsp110 is induced by heat shock and its induction is associated with thermotolerance. The sequence
of Hsp110 reportedly bears similarity to several Hsp70-related proteins that have been termed Hsp110/SSE. The carboxy-terminal domains of
these proteins and Hsp110 contain a putative peptide-binding site. These proteins also contain six highly conserved regions found in the same
progression, as well as five conserved ATP-binding motifs.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.