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Rab3 Pure 9/Rab3 50ug

  • 产品编号:BD-610379      品牌:BD-Pharmingen       原厂货号:610379
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 50ug
运保温度: Store undiluted at -20°C .
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标准价: ¥客户可见
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描述:

RCC1 (Regulator of Chromosome Condensation) is a chromatin-associated protein implicated in a number of cellular processes such as nuclei
formation, initiation/termination of transcription, pre-mRNA splicing/3'-end formation, mRNA export and DNA replication. Normally, RCC1
appears to play a structural role with chromatin. This nuclear protein can function as a guanine nucleotide exchange factor for the Ras-like
GTPase, Ran/TC4. Loss of RCC1 expression is related to a structural transition of the chromosome and correlates with the inability of the cells
to detect unreplicated DNA. RCC1 appears to be necessary for nucleocytoplasmic transport of precursors of spliceosomal small nuclear RNAs
(snRNAs), intranuclear transport of U3 snRNA and processing of ribosomal RNAs, but not for export of transfer RNAs.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at -20°C .


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