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Neuronal Pentraxin Pure 22 50ug

  • 产品编号:BD-610369      品牌:BD-Pharmingen       原厂货号:610369
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 50ug
运保温度: Store undiluted at -20°C .
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描述:

Neuronal pentraxin (NP) is a potential receptor for the snake venom toxin, taipoxin. The highest levels of NP
mRNA are found in the
cerebellum and the CA3 region of the hippocampus. More specifically,NP
mRNA is expressed at high levels in Purkinje and granule neurons
of the cerebellum and CA3 neurons of the hippocampus. Moderate levels are present in neurons of the hilus, dentate gyrus, CA1, cerebral
cortex, medial habenula, anterior hypothalamic nuclei, olfactory cortex, and inferior olivary nuclei.
NP mRNA is not expressed in glia of white
or gray matter. It is thought that NP serves as a receptor for taipoxin and, after binding, NP-taipoxin is taken into presynaptic terminals.
Alternatively, the binding of taipoxin by NP may represent a nonspecific mechanism to sequester toxins from synapses.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at -20°C .


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