RPTP Alp Pure 21 50ug

产品编号：BD-610348 品牌：BD-Pharmingen 原厂货号：610348
产品分类：抗体 > 一抗 > 蛋白特异性一抗
应用分类：

包装：

50ug

运保温度:

Store undiluted at -20°C .

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描述：

Receptor-like protein tyrosine phosphatases (RPTPs) represent an important pathway for signal transduction via modification of protein

tyrosine phosphorylation status. RPTPα is widely expressed and is particularly abundant in brain. Structurally, it is typical of RPTPs in that it

has an intracellular region containing two tandem catalytic domains linked to a transmembrane and an extracellular region. However, unlike

many RPTPs, the extracellular region of RPTPα is small (123 residues) and lacks any obvious structural motifs, though the protein is known

to be heavily glycosylated. Both catalytic domains of RPTPα have intrinsic in vitro activity, but their exact roles in vivo remain uncertain. It

has been postulated that due to their transmembrane nature, RPTPs are initiators for a cascade of intracellular signaling events, much like

receptor tyrosine kinases.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at -20°C .