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Hu CD20 BV510 H1 50Tst

  • 产品编号:BD-563347      品牌:BD-Pharmingen       原厂货号:563347
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 50Tst
运保温度: Store undiluted at 4°C
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描述:

The H1 (FB1) antibody specificially binds to a cytoplasmic domain of CD20. CD20 is a 33-37-kDa four transmembrane phosphoprotein that
is expressed by B lymphocytes from the pre-B stage and most malignant B cells and is lost during plasma cell differentiation. Low level CD20
expression is observed on a subset of normal circulating T lymphocytes, and CD20-positive T-cell lymphomas have been reported. The CD20
molecule is associated with membrane lipid raft domains, acts as a channel for calcium ions, and is involved in the regulation of B cell
activation and survival. The cytoplasmic domain regions are serine and threonine rich and contain multiple phosphorylation consensus
sequences.
The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max
of 405-nm and Em Max at 510-nm, BD Horizon™ BV510 can be excited by the violet laser and detected in the BD Horizon™ V500
(525/50-nm) filter set. BD Horizon™ BV510 conjugates are useful for the detection of dim markers off the violet laser.
 


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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