Hu CD146 BV711 P1H12 50Tst

• 产品编号：BD-563186      品牌：BD-Pharmingen       原厂货号：563186
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

The P1H12 monoclonal antibody specifically binds to CD146. CD146 is a 118 kDa transmembrane glycoprotein also known as MCAM,
MUC18, or Mel-CAM. CD146 is a member of the immunoglobulin superfamily and is expressed by angioblasts and mesenchymal stems cells
and is strongly expressed by blood vessel endothelium and smooth muscle. CD146 is also expressed by melanoma cells, intermediate
trophoblasts and a subpopulation of activated T cells. The P1H12 monoclonal antibody has been reported to block endothelial cell adhesion
that is observed very early in embryogenesis. It can be useful in the study of embryologic vasculogenesis. This antibody is suitable for
immunohistochemical staining of acetone-fixed frozen tissue sections, immunoprecipitation and ELISA.
The antibody was conjugated to BD Horizon BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem
fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 711-nm. BD Horizon BV711 can be
excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor® 700-like dyes (eg, 712/20-nm filter). Due to the
excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor® 700 and PerCP-Cy5.5
detectors. However, the spillover can be corrected through compensation as with any other dye combination.

原厂资料：

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.