Ms IL-2 BV421 JES6-5H4 50ug

产品编号：BD-562969 品牌：BD-Pharmingen 原厂货号：562969
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

50ug

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The JES6-5H4 monoclonal antibody specifically binds to mouse interleukin-2 (IL-2). IL-2 is a multifunctional cytokine that plays pivotal
roles in immunity and tolerance. It is produced by activated T cells. IL-2 effects the activation, growth, proliferation and/or differentiation of
various cell types including T and B lymphocytes and their precursors, LAK cells, NK cells, and monocytes/macrophages. IL-2 mediates its
biological activities by binding to IL-2 receptor compleses. The intermediate affinity IL-2R is comprised of IL-2Rβ (CD122) and common
gamma chain (γc; CD132) subunits whereas the high-affinity IL-2R is comprised of IL-2Rα (CD25), IL-2Rβ and γc subunits. The JES6-5H4
monoclonal antibody binds to IL-2 and neutralizes its biological activity.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max
of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter
set (eg, 450/50-nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared
to Pacific Blue™ conjugates.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.