Hu CD132 BV421 AG184 50Tst

产品编号：BD-562881 品牌：BD-Pharmingen 原厂货号：562881
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

50Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The AG184 monoclonal antibody specifically binds to the 65-70 kDa common γ subunit (γc) that is shared by the IL-2, IL-4, IL-7, IL-9,
IL-15 and IL-21 receptor complexes. The γc receptor is a type 1 transmembrane glycoprotein that is constitutively expressed by most
peripheral T and B lymphocytes, NK cells, monocytes and granulocytes. The cytoplasmic domain of the γc chain plays an important role in
cytokine-mediated signal transduction. By immunofluorescent staining and flow cytometric analyses, the AG184 antibody has been shown to
specifically recognize human γc expressed by cell lines including human γc gene-transfected cell lines which are known to express the human
γc chain. The AG184 antibody can bind the γc chain in the receptors complexed with IL-2, IL-4, or IL-7, indicating that the antibody
recognizes an epitope which is distinct from the cytokine binding site of the γc chain.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max
of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter
set (eg, 450/50-nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to
Pacific Blue™ conjugates.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.