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Ms CD282 Alexa 647 6C2 50ug

  • 产品编号:BD-562625      品牌:BD-Pharmingen       原厂货号:562625
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 50ug
运保温度: Store undiluted at 4°C
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描述:

The 6C2 monoclonal antibody specifically binds to the mouse Toll like receptor 2 (TLR2) that is also known as CD282. CD282 is a type 1
transmembrane glycoprotein and a TLR family member. It is expressed on the surface of monocytes, macrophages, dentritic cells,
granulocytes, endothelial and epithelial cells. This pattern recognition receptor is important for sensing and transducing signals in response to
microbial cell wall components including lipoproteins, peptidoglycans and lipoteichoic acid. CD282 signals through intracellular MYD88 and
TRAF6 leading to NF-kappa-B activation and the production of cytokines and inflammatory mediators by responding cells. TLR2 plays a
major role in mediating inflammatory and innate immune responses.
 


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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