Hu CD38 BV421 HIT2 100Tst

• 产品编号：BD-562444      品牌：BD-Pharmingen       原厂货号：562444
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

The HIT2 monoclonal antibody specifically binds to CD38. CD38 is a 45 kDa type II single-chain transmembrane glycoprotein present on
thymocytes, activated T cells and terminally differentiated B cells (plasma cells). Other reactive cells include monocytes, macrophages,
dendritic cells and some epithelial cells. The CD38 antigen acts as an ectoenzyme that catalyzes the synthesis and hydrolysis of a Ca++
mobilizing agent, cyclic ADP-ribose. This intracellular calcium plays an important role in cell signaling pathways. Reports describe CD38 as
participating in adhesion with CD31, immunoregulatory functions involving signal transduction leading to cell growth, apoptosis, and
differentiation.
The antibody was conjugated to BD Horizon™ BV421 which is part of the BD Horizon™ Brilliant Violet™ family of dyes. With an Ex Max
of 407-nm and Em Max at 421-nm, BD Horizon™ BV421 can be excited by the violet laser and detected in the standard Pacific Blue™ filter
set (eg, 450/50-nm filter). BD Horizon™ BV421 conjugates are very bright, often exhibiting a 10 fold improvement in brightness compared to
Pacific Blue™ conjugates.

原厂资料：

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.