Hu CD117 PE-CF594 YB5.B8 50Tst

• 产品编号：BD-562407      品牌：BD-Pharmingen       原厂货号：562407
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

The YB5.B8 monoclonal antibody specifically binds to CD117. CD117, also known as c-Kit, is a 145 kDa cell-surface glycoprotein with
tyrosine kinase activity. CD117 is present on hematopoietic progenitor cell subsets, thymocytes, mast cells, hepatocytes and histiocytes.
CD117 serves as a cytokine receptor for steel factor (SLF), also known as stem cell factor (SCF) or mast cell growth factor (MGF). The
interaction of c-Kit and SLF is crucial to hematopoiesis, mast cell differentiation, melanogenesis, and germ cell development. The ability of
the YB5.B8 antibody to block the binding of c-Kit ligand is still controversial.
This antibody is conjugated to BD Horizon™ PE-CF594, which has been developed exclusively by BD Biosciences as a better alternative to
PE-Texas Red®. PE-CF594 excites and emits at similar wavelengths to PE-Texas Red® yet exhibits improved brightness and spectral
characteristics. Due to PE having maximal absorption peaks at 496 nm and 564 nm, PE-CF594 can be excited by the blue (488-nm), green
(532-nm) and yellow-green (561-nm) lasers and can be detected with the same filter set as PE-Texas Red® (eg 610/20-nm filter).
 

原厂资料：

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.