Ms CD70 NALE FR70 500ug

• 产品编号：BD-562226      品牌：BD-Pharmingen       原厂货号：562226
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

描述：

The FR70 monoclonal antibody specifically binds to mouse CD70, a 30-33 kDa type-II transmembrane glycoprotein. CD70 belongs to the
TNF superfamily and is also known as tumor necrosis factor ligand superfamily member 7 (Tnfsf7). CD70 is the ligand for CD27 and is
expressed primarily on activated B cells and dendritic cells and at low levels by some activated T cells. The CD27-CD70 interaction delivers
costimulatory signals to T-cells and NK cells that can augment their proliferative, cytokine production, and cytotoxicity responses. It has been
reported that FR70 mAb blocks the binding of CD70 to CD27 and inhibits some humoral and cell-mediated immune responses that depend on
costimulated T cells, NK cells or both.
 

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Store undiluted at 4°C.