Ms CD45 PE-Cy5 30-F11 25ug

• 产品编号：BD-561870      品牌：BD-Pharmingen       原厂货号：561870
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

原厂资料：

The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and
all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the
cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase
(PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly
variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell
and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation
state-specific.

注意事项：

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.PE-Cy5 is optimized for use with a single argon ion laser emitting 488-nm light. Because of the broad absorption spectrum of the PE-Cy5 tandem fluorochrome, extra care must be taken when using dual-laser cytometers which may directly excite both PE and Cy5™.

4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
6.The antibody was conjugated with PE-Cy5 (formerly known as BD Cy-Chrome™) under optimum conditions, and unconjugated antibody and free PE-Cy5 were removed.