Ms CD54 APC 3E2 50ug

• 产品编号：BD-561605      品牌：BD-Pharmingen       原厂货号：561605
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

原厂资料：

The 3E2 antibody reacts with CD54 (ICAM-1), a 95-kDa member of the Ig superfamily found on lymphocytes, vascular endothelium, high
endothelial venules, epithelial cells, macrophages, and dendritic cells. ICAM-1 is a ligand for LFA1 (CD11a/CD18) and Mac-1
(CD11b/CD18). Its expression is upregulated upon stimulation by inflammatory mediators such as cytokines and LPS. Studies with mouse
Icam1-transfected antigen-presenting cells, with CD54-blocking antibodies, and in CD54-deficient mice indicate that CD54 participates in
inflammatory reactions and antigen-specific immune responses. In addition, there is evidence that CD54 is a receptor involved in
MHC-non-restricted responses to weakly immunogenic tumor cells. The 3E2 antibody has been reported to block in vitro and in vivo
intracellular adhesion events involved in immune responses.

注意事项：

1.ince applications vary, each investigator should titrate the reagent to obtain optimal results.
2.This APC-conjugated reagent can be used in any flow cytometer equipped with a dye, HeNe, or red diode laser
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
4.An isotype control should be used at the same concentration as the antibody of interest.
5.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
6.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
7.The antibody was conjugated to APC under optimum conditions, and unconjugated antibody and free APC were removed