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Hu CD80 Alexa 700 L307.4 50Tst

  • 产品编号:BD-561133      品牌:BD-Pharmingen       原厂货号:561133
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 50Tst
运保温度: Store undiluted at 4°C
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描述:

The L307.4 monoclonal antibody specifically reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the
Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on
activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80
is also expressed on activated CD4-positive and CD8-positive T cells, appearing late after activation suggesting that activated T cells may be
capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell
activation and a signal for IL-2 production.


注意事项:

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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