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Hu CD80 PE L307.4 25Tst

  • 产品编号:BD-560925      品牌:BD-Pharmingen       原厂货号:560925
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 25Tst
运保温度: Store undiluted at 4°C
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描述:

The L307.4 monoclonal antibody specifically reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the
Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on
activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80
is also expressed on activated CD4-positive and CD8-positive T cells, appearing late after activation suggesting that activated T cells may be
capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell
activation and a signal for IL-2 production.


注意事项:


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.


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