Hu CD197 (CCR7) Hrzn V450 150503 120Tst

产品编号：BD-560863 品牌：BD-Pharmingen 原厂货号：560863
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

120Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The monoclonal antibody 150503 specifically binds to the human CC chemokine receptor, CCR7, also known as CD197. CCR7 (previously
known as BLR2, EBI1 and CMKBR7), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokines,
MIP-3β/Exodus 3/ELC/ CCL19 and 6Ckine/Exodus 2/SLC/TCA4/CCL21. CCR7 mRNA is expressed mainly in lymphoid tissues including
spleen, lymph nodes and tonsil. CCR7 is expressed on peripheral T and B lymphocytes, by bone marrow and cord blood CD34-positive cells
and by mature dendritic cells. Differential CCR7 expression can be used to distinguish naive, central memory and effector memory T cell
subsets. The human CCR7 gene, unlike other CC chemokine receptor genes, has been mapped to chromosome 17 (region 17q12).
The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is
available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406 nm and has an Em Max at 450 nm. Conjugates with
BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.