Hu CD80 Horizon V450 L307.4 30Tst

• 产品编号：BD-560444      品牌：BD-Pharmingen       原厂货号：560444
• 产品分类：抗体 > 一抗 > 染料标记抗体
• 应用分类：

描述：

The L307.4 monoclonal antibody specifically reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the
Fifth International Workshop on Human Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on
activated B cells, macrophages, and dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80
is also expressed on activated CD4-positive and CD8-positive T cells, appearing late after activation suggesting that activated T cells may be
capable of autocrine costimulation via the CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell
activation and a signal for IL-2 production.
The antibody is conjugated to BD Horizon™ V450, which has been developed for use in multicolor flow cytometry experiments and is
available exclusively from BD Biosciences. It is excited by the Violet laser Ex max of 406 nm and has an Em Max at 450 nm. Conjugates with
BD Horizon™ V450 can be used in place of Pacific Blue™ conjugates.

原厂资料：

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.