Ms RANKL/TRANCE Alexa 647 IK22-5 100ug

产品编号：BD-560296 品牌：BD-Pharmingen 原厂货号：560296
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100ug

运保温度:

Store undiluted at 4°C

到货周期：

登录后查看

标准价：

￥客户可见

会员价：

￥客户可见

积分：

客户可见分

登录之后可加入购物车购买，请您

运费与支付说明：

1.含干冰类产品有运费；

2. 必须现金付款或有信用额度的会员才可以直接发货，否则需要等待现金付款信息。

描述：

TRANCE/RANKL/OPGL/ODF is a recently identified member of the tumor necrosis factor family. TRANCE (TNF-Related
Activation-Induced Cytokine Receptor) or RANKL (Receptor Activator of NF-kB Ligand) has been implicated in interactions between T cells
and dendritic cells. TRANCE/RANKL binds to RANK on dendritic cells, upregulates the expression of anti-apoptotic protein BcL-XL
suggesting a role in dendritic cell survival. TRANCE/RANKL is also important in T- and B-cell maturation. As OPGL/ODF (Osteoprotegerin
Ligand/Osteoclast Differentiation Factor), the same protein can both activate mature osteoclasts and mediate osteoclastogenesis.
OPGL/TRANCE deficient mice show severe osteoporesis and complete absence of osteoclasts as a result of lack of osteogenesis. It is
expressed abundantly by mouse activated T cells, not B cells. It is also expressed on osteoclasts.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.