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Hu CD8 APC-H7 SK1 25Tst

  • 产品编号:BD-560273      品牌:BD-Pharmingen       原厂货号:560273
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 25Tst
运保温度: Store undiluted at 4°C
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描述:

CD8 recognizes the 32-kDa a-subunit of a disulfide-linked bimolecular complex. The majority of peripheral blood CD8+ T lymphocytes
express an a/b heterodimer (Mr 32, 30 kDa), while CD8+CD16+ natural killer (NK) lymphocytes and CD8+ T-cell receptor (TCR)-γ/δ+
lymphocytes express a/a homodimer (Mr 30 kDa). CD8+TCR-α/β+ lymphocytes can express either an α/α homodimer or α/β heterodimer. The
CD8 antigenic determinant binds to class I major histocompatibility (MHC) molecules resulting in increased adhesion between the CD8+ T
lymphocytes and target cells. Binding of the CD8 antigen is coupled to a protein tyrosine kinase p56lck. The CD8:p56lck complex can play a
role in T-lymphocyte activation through mediation of the interactions between the CD8 antigen and the CD3/TCR complex.


注意事项:

 


1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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