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Cytochrome c Alexa 488 6H2.B4 100Tst

  • 产品编号:BD-560263      品牌:BD-Pharmingen       原厂货号:560263
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

A cytochrome is an electron-transporting protein that contains a heme prosthetic group. Cytochromes have been known to be essential
components of the mitochondrial respiratory chain since 1925. The iron atom of the heme group in cytochromes alternates between a reduced
ferrous (+2) state and an oxidized ferric (+3) state during electron transport in oxidative phosphorylation. Cytochromes are classified into four
groups (a, b, c and d) according to spectrochemical characteristics, and there are five cytochromes between coenzyme QH2 and O2 in the
electron transport chain. Cytochrome c is a water-soluble protein that either promotes cell survival or death, depending upon its intracellular
location. In healthy cells, it is a peripheral membrane protein of the mitochondria that transports electrons from the coenzyme QH2
cytochrome c reductase complex to the cytochrome c oxidase complex. When proapoptotic stimuli induce breakdown of the mitochondria,
cytochrome c is released to the cytosol where it functions in the activation of caspases that trigger apoptosis.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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