Hu CD39 APC TU66 100Tst

产品编号：BD-560239 品牌：BD-Pharmingen 原厂货号：560239
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The TU66 monoclonal antibody reacts with human CD39 also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1) an
ectoenzyme that degrades ATP to AMP. It is a member of the family of ectonucleoside triphosphate dihydrolases (E-NTPDases) known to be
involved in regulation of extracellular nucleotide catabolism, controlling the extracellular nucleoside triphosphate pool (NTP). CD39 is
expressed on a subset of T cells, B cells and dendritic cells with weak staining of monocytes and granulocytes. Recently, CD39 has been found
to be expressed primarly by immune-suppressive Foxp3(+) regulatory T (Treg) cells in both human and mice. In humans, CD39 is restricted to
a subset of Foxp3+ regulatory effector/memory-like T cells. In mice, the enzyme is present on most if not all CD4+CD25+ cells and CD39
expression is driven by Foxp3. It is thought that CD39 allows Treg cells to enter inflamed areas where high levels of ATP are present.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 X 10e6 cells in a 100-μl experimental sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The antibody was conjugated with APC under optimum conditions, and unconjugated antibody and free APC were removed.