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Hu TRA-1-60 Ag Alexa 555 TRA-1-60 100Tst

  • 产品编号:BD-560121      品牌:BD-Pharmingen       原厂货号:560121
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

The TRA-1-60 monoclonal antibody reacts with the neuraminidase-resistant form of a pluripotent-stem-cell-specific epitope on a
high-molecular-weight transmembrane glycoprotein. The TRA-1-60 antigen is a sialylated epitope on the same keratan sulfate core molecule,
podocalyxin, as 4 other distinct antigens on tumor-derived cell lines, TRA-1-81, GCTM2, K4, and K21. The expression of TRA-1-60 antigen
is stage-specific and can be used to characterize embryonic cells and monitor their differentiation. The antigen is found on teratocarcinoma
(embryonal carcinoma or EC), embryonic inner cell mass (but not morula or trophoblast), and embryonic stem (ES) cells. TRA-1-60 antigen
is released into the serum of patients bearing testicular tumors containing EC cells. As human EC and ES cells undergo differentiation,
expression of TRA-1-60 antigen is lost. Expression of TRA-1-60 antigen has also been observed on a rhesus monkey ES cell line (Thomson
et al, 1995).


注意事项:

 

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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