GAD65 Pure GAD-6 100ug

• 产品编号：BD-559931      品牌：BD-Pharmingen       原厂货号：559931
• 产品分类：抗体 > 一抗 > 蛋白特异性一抗
• 应用分类：

描述：

γ-aminobutyric acid (GABA) is an amino acid neurotransmitter that is considered to be the major inhibitory neurotransmitter in the
mammalian central nervous system. The highest concentrations of GABA are found in the brain, where it is synthesized from glutamic acid to
GABA by an enzyme called glutamic acid decarboxylase (GAD). GAD is also expressed in the insulin-producing β cells of the islets of
Langerhans. Two isoforms of GAD are present in rat brain, GAD65 and GAD67, based on their relative molecular weight in kDa. Both
isoforms have significant levels of homology in the catalytic portion of the molecule, but differ greatly in the first 95 amino acids in the
N-terminal region. GAD65 migrates at ~65 kDa in SDS/PAGE. The antibody is reported to recognize rat, human, mouse, and pig GAD65.
Purified GAD65 from rat brain was used as the immunogen. The specific epitope recognized by this clone is a linear epitope localized in the
last 41 amino acids of GAD65.

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.