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Hu CD196 (CCR6) Biotin 11A9 500ug

 
包装: 500ug
运保温度: Store undiluted at 4°C
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描述:

The monoclonal antibody 11A9 reacts with the human CC chemokine receptor, CCR6. CCR6 (previously known as BN-1, CKR-L3, DRY6,
GPR-CY4 and STRL22), a seven-transmembrane, G-protein-coupled receptor, is the specific receptor for CC chemokine MIP-3a/LARC/
Exodus. It has been shown that CCR6 mRNA is expressed mainly in lymphoid tissues including spleen, lymph nodes, thymus, appendix.
CCR6 mRNA was also detected in peripheral T- and B-lymphocytes and in CD34-derived dendritic cells. The human CCR6 gene, unlike other
CCR genes, has been mapped to chromosome 6q27. The immunogen used to generate 11A9 hybridoma was KLH-conjugated N-terminus
peptides of human CCR6. It does not cross-react with human CCR1, CCR2, CCR3, CCR4, CCR5, CCR7, CCR8, CCR9, CXCR1, CXCR2,
CXCR3, CXCR4 and CXCR5 transfectants. This antibody is NOT a neutralizing antibody. CCR6 had been clustered as CD196 in the VIIIth
HLDA workshop.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing. .
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.


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