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Ms Rat CD81 PE Eat2 100ug

  • 产品编号:BD-559519      品牌:BD-Pharmingen       原厂货号:559519
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C
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描述:

The Eat2 antibody reacts with CD81, a 26-kDa nonglycosylated member of the transmembrane 4 integral membrane protein superfamily,
expressed by many types of cells. For example, CD81 participates with CD19 and CD21 in the signal transduction complex associated with
the B-cell receptor on human B lymphocytes and with the CD4 and CD8 co-receptors on human thymocytes and T lymphocytes. In mouse
fetal thymic organ culture, interactions of immature thymocytes with CD81 expressed by thymic stromal cells are required to induce
development of T cells with αβ T-cell receptors. Furthermore, CD81 has been shown to play a role in the regulation of rat mastcell
degranulation. Despite its important roles in the immune response and wide tissue distribution, CD81-deficient mice are born without obvious
developmental abnormalities. However, these mice have abnormal immune responses, and impaired fertility. Eat2 mAb cross-reacts with the
rat CD81 antigen.


注意事项:


1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.


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