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Hu CD119 PE GIR-94 200ug

  • 产品编号:BD-558937      品牌:BD-Pharmingen       原厂货号:558937
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 200ug
运保温度: Store undiluted at 4°C
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描述:

The GIR-94 antibody recognizes the extracellular region of the alpha chain subunit (80-95 kDa glycoprotein) of the human interferon-γ
receptor (IFN-γRα; aka, CD119). The functionally active-form of the human IFN-γ receptor consists of two (or more) subunits, with IFN-γRα
responsible for IFN-γ binding and both the IFN-γR α and β chains required for the transduction of biologic responses. The IFN-γ receptor α
chain (CD119) is expressed on the surface of most human cells (except mature erythrocytes) including monocytes, macrophages, T cells, B
cells, NK cells, neutrophils, fibroblasts, epithelial cells, and endothelium. The ability of this antibody to bind to IFN-γ receptors of species
other than human has not been determined. The immunogen used to generate this hybridoma was human IFN-γRα purified from human
placenta. The GIR-94 is a non-neutralizing antibody.


注意事项:


1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.


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