Hu CD123 PerCP-Cy5.5 7G3 100Tst

产品编号：BD-558714 品牌：BD-Pharmingen 原厂货号：558714
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100Tst

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The 7G3 monoclonal antibody specifically reacts with human CD123, the 70 kD IL-3 receptor α chain (IL-3Rα), which associates with the
120-140 kD β subunit. The β chain is shared with the receptors for interleukins IL-5 and GM-CSF. IL-3Rα is expressed on hematopoietic
progenitors and plays an important role in hematopoietic progenitor cell growth and differentiation. This antibody has been reported to block
the binding of 125I-IL-3 to high and low affinity IL-3 receptors. In functional experiments, this antibody was found to inhibit acute myeloid
leukemia cell proliferation, basophil histamine release, endothelial cell-mediated IL-8 secretion, and neutrophil transmigration. This antibody
has been reported to be useful for immunoprecipitation, western blot and immunofluorescent staining for flow cytometry. At the Fifth HLDA
Workshop, the human IL-3 receptor was designated CD123.

注意事项：

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.