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Hu CD336 Alexa 647 P44-8.1 100Tst

  • 产品编号:BD-558564      品牌:BD-Pharmingen       原厂货号:558564
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

The p44-8 monoclonal antibody specifically binds to the natural killer (NK) cell receptor, NKp44, which is also known as CD336, Natural
cytotoxicity triggering receptor 2 (NCR2), or Lymphocyte antigen 95 homolog (Ly95). NKp44 is a ~44 kDa type I transmembrane protein that
belongs to the natural cytotoxicity receptor (NCR) family within the immunoglobulin superfamily. NKp44 is expressed by activated NK cells.
NKp44 serves as an activating receptor that can enhance NK cell mediated lysis of target cells including tumor cells and virus-infected cells.
Killer activating receptor associated protein (KARAP), which is also known as DAP12, is an intracellular adaptor protein that can associate
with the intracellular region of NKp44. DAP12 can then function to help transmit activating signals through its immunoreceptor
tyrosine-based activation motif (ITAM).


注意事项:

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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