BD IMag™ anti-rat CD4 Particles - DM are magnetic nanoparticles that have monoclonal antibody conjugated to their surfaces. These
particles are optimized for the positive selection or depletion of CD4-bearing T lymphocytes using the BD IMagnet™. The OX-38 antibody
reacts with the CD4 antigen on most thymocytes, a subpopulation of mature T lymphocytes (i.e., MHC class II-restricted T cells, including
most T helper cells), monocytes, macrophages, and some dendritic cells. CD4 is an antigen coreceptor on the T-cell surface that interacts with
MHC class II molecules on antigen-presenting cells. It participates in T-cell activation through its association with the T-cell receptor complex
and protein tyrosine kinase lck. Rat thymocyte glycoproteins were used as the source of immunogen.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Store undiluted at 4°C.