Hu CD183 Alexa 488 1C6/CXCR3 100ug

包装：

100ug

运保温度:

Store undiluted at 4°C

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描述：

Clone 1C6/CXCR3 reacts with the human form of the 40 - 41 kDa seven-transmembrane protein and member of the G protein-coupled

receptor family. CXCR3 is expressed primarily on activated T cells that infiltrate inflammatory sites. It has also been detected on some

circulating T cells, B cells, and NK cells. Reports show that some CXCR3 T cells also express CCR5 and are mostly CD45RO cells. Three

ligands for CXCR3 have been identified. They are interferon-γ inducible 10-kD protein (IP-10), monokine induced by interferon-γ (MIg), and

interferon-inducible T-cell γ chemoattractant (I-TAC). These chemokines are produced by a variety of cells upon stimulation by IFN γ and

interact with CXCR3 to mediate T-cell chemotaxis. This reagent has been reported to be suitable for immunohistochemical staining of

acetone-fixed, frozen sections and/or formalin-fixed, paraffin-embedded tissue sections with citrate pretreatment. Clone CXCR3 also cross

reacts with a subset of peripheral blood lymphocytes of baboon, and both rhesus and cynomolgus macaque monkeys. The distribution of

lymphocytes is similar to that observed with peripheral blood lymphocytes from normal human donors. CXCR3 has been clustered as CD183

in the VIIth HLDA workshop.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.