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c-Jun (pS63) Pure 2/c-Jun/(S63) 100ug

  • 产品编号:BD-558036      品牌:BD-Pharmingen       原厂货号:558036
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at -20°C
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描述:

The activator protein transcription factor (AP-1) was identified as a protein that recognizes specific sequences in the cis-control regions of the
SV40 virus and the human metallothionein IIA gene. AP-1 is composed of protein products of two different gene families: jun and fos. The
AP-1 transcription factor is either a homodimer of Jun proteins or a heterodimer of Jun and Fos proteins. The transcriptional activity of Jun is
enhanced by phosphorylation of serines 63 (S63) and 73 in its activation domain. Phosphorylation at both sites is necessary for stimulating
the activating function of Jun. Jun is phosphorylated by JNK protein kinases that are activated by the same signals that potentiate Jun activity.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at -20°C.


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