Hu CD45RO IMag Particles-DM UCHL1 5mL

• 产品编号：BD-557986      品牌：BD-Pharmingen       原厂货号：557986
• 产品分类：生化和细胞分析 > 微珠和磁珠 > 细胞分选磁珠 > 分离人细胞
• 应用分类：

描述：

BD IMag™ Anti-Human CD45RO Particles - DM are magnetic nanoparticles that have monoclonal antibody conjugated to their surfaces.
These particles are optimized for the positive selection of CD45RO-bearing leukocytes using the BD IMagnet™ (Cat. No. 552311). CD45RO
is the 180 kDa isoform of leukocyte common antigen that is not encoded by exon A, B, or C and found on most thymocytes, activated T
lymphocytes, granulocytes, and monocytes and on a major subset of peripheral T lymphocytes. CD45RO and CD45RA expression defines
complementary, predominantly non-overlapping populations of T cells in peripheral blood; and it is generally accepted that naive T cells are
CD45RO- CD45RA+, while memory T cells are CD45RO+ CD45RA-. To specifically enrich CD45RO-expressing memory T lymphocytes,
we recommend first depleting the erythrocytes, platelets, and non-T leukocytes, by using the appropriate BD IMag™ human T lymphocyte
enrichment set, followed by positive selection of the CD45RO+ population (please refer to the following protocol).

原厂资料：

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.