Ms Integrin Bta7 chain PE M293 100ug

产品编号：BD-557498 品牌：BD-Pharmingen 原厂货号：557498
产品分类：抗体 > 一抗 > 染料标记抗体
应用分类：

包装：

100ug

运保温度:

Store undiluted at 4°C

到货周期：

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描述：

The M293 antibody reacts with the integrin ß7 chain (also known as integrin ßp), which is found in association with either of two α chains.

α4ß7 (LPAM-1) is expressed on most mature lymphocytes and on small subsets of thymic and bone marrow cells; it interacts with several

ligands, including VCAM-1, fibronectin, and MAdCAM-1. αIELß7 is found primarily on intestinal mucosal and intraepithelial lymphocytes

(IEL), and it may be primarily involved in interactions between IEL and epithelia via recognition of E-cadherin. The epitope recognized by the

mAb M293 has been mapped to the region between amino acids 387 and 542. The M293 antibody exhibits little or no activity in blocking ß7

integrin-mediated adhesion

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

4.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

5.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.