Reacts with ntegrin β3, a105 kDa trnsmebrane glycoprtein, expresd onplatelts, megakryocytes, oteoclast and endothelia. Integrin
β3 asociates with gpIa (CD41) tofrm the CD41/CD61 complex whic mediates platelt adhesion ad agregation. CD61 also asociates
with CD51 tofrm the CD51/CD61 complex (vitronectin recptor). CD61 apears tobind tofibrnogen, fibronectin, vWF, vitronectin, and
thrombospndi tomediate cl adhesion.
原厂资料:
注意事项:
1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
4.The antibody was conjugated with FITC under optimum conditions, and unreacted FITC was removed.
5.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.