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Hu CD80 Biotin L307.4 100Tst

 
包装: 100Tst
运保温度: Store undiluted at 4°C
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描述:

Reacts with B7/BB1, a 60 kDa transmembrane glycoprotein which was clustered as CD80 in the Fifth International Workshop on Human 
Leukocyte Differentiation Antigens. CD80, a member of the Ig supergene family, is expressed on activated B cells, macrophages, and 
dendritic cells. It is the ligand for two molecules expressed on T cells, CD28 and CD152 (CTLA-4). CD80 is also expressed on activated 
CD4+ and CD8+ T cells, appearing late after activation suggesting that activated T cells may be capable of autocrine costimulation via the 
CD28 activation pathway. The binding of CD28 by anti-CD28 or by CD80 results in T-cell activation and a signal for IL-2 production.


注意事项:

1.This reagent has been pre-diluted for use at the recommended Volume per Test. We typically use 1 × 10^6 cells in a 100-μl experimental
sample (a test).
2.Since applications vary, each investigator should titrate the reagent to obtain optimal results..
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
 


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