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Rat CD45RA PE-Cy5 OX-33 100ug

  • 产品编号:BD-557015      品牌:BD-Pharmingen       原厂货号:557015
  • 产品分类:抗体 > 一抗 > 染料标记抗体
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C
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描述:

The OX-33 antibody reacts with a high-molecular-weight form of CD45 found only on B lymphocytes. CD45 is a member of the Protein
Tyrosine Phosphatase (PTP) family: Its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region
is highly variable due to alternative splicing of exons 4, 5, and 6 (designated A, B, and C, respectively), plus differing levels of glycosylation.
The CD45 isoforms detected in the rat are cell type-, maturation-, and activation state-specific. The CD45 isoforms play complex roles in
T-cell and B-cell antigen receptor signal transduction.


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.PerCP-Cy5.5–labelled antibodies can be used with FITC- and R-PE–labelled reagents in single-laser flow cytometers with no significant spectral overlap of PerCP-Cy5.5, FITC, and R-PE fluorescence.
3.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
5.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
6.The antibody was conjugated with PerCP-Cy5.5 under optimum conditions, and unconjugated antibody and free PerCP-Cy5.5 were removed. Storage of PerCP-Cy5.5 conjugates in unoptimized diluent is not recommended and may result in loss of signal intensity
 


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