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Hu P-glycoprotein Pure 17F9 100ug

  • 产品编号:BD-557001      品牌:BD-Pharmingen       原厂货号:557001
  • 产品分类:抗体 > 一抗 > 蛋白特异性一抗
  • 应用分类:
 
包装: 100ug
运保温度: Store undiluted at 4°C.
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描述:

The 17F9 monoclonal antibody specifically binds to the 170-180 kDa transmembrane glycoprotein (P-glycoprotein), a product of the 
multidrug resistance-1 (MDR1) gene. This glycoprotein is expressed on MDR positive cells and has been reported to be expressed on many 
normal tissues, such as adrenal glands and endothelium, in the brain and skin. P-glycoprotein is known to impart drug resistance to cells by 
pumping many anti-cancer drugs out of the cytoplasm. 17F9 antibody is able to partially block the binding of UIC2 antibody (another 
MDR-specific monoclonal antibody). Immunoprecipitation application is reported, but not routinely tested in house.
 


注意事项:

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before
discarding to avoid accumulation of potentially explosive deposits in plumbing.
3.Store undiluted at 4°C.
 


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