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Hu Fas:Fc Chimeric Fusion Protein 100ug

 
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运保温度: Store product at -80°C
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描述:

Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand
(FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissues and
cells including the thymus, liver, ovary and lung. FasL is a member of the TNF cytokine family that induces apoptosis by binding to Fas, its
cell-surface receptor. FasL may exist as either membrane-bound or soluble forms and is expressed by activated T and NK cells. Both Fas and
FasL are thought to play an important role in the apoptotic processes that take place during T cell development.
Human Fas:Fc fusion protein is comprised of the extracellular domain of the Fas receptor fused to the Fc portion of human IgG1 as described
by Brunner et. al. The protein was produced in the Baculovirus Expression Vector System (BEVS) and was purified by affinity
chromatography. Molecular weight of Fas:Fc fusion protein is 50 kDa.


注意事项:

This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Store product at -80°C prior to use or for long term storage of stock solutions.
Avoid multiple freeze-thaw cycles to prevent protein degradation.


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