Hu Clk1 Pure G313-1 100ug

包装：

100ug

运保温度:

Store undiluted at 4°C.

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描述：

Clk (also referred to as Sty) is a mammalian protein kinase that phosphorylates both serine/threonine and tyrosine residues. It belongs to the

LAMMER family of dual specificity kinases that also includes KNS1 (from Saccharomyces cerevisiae), AFC (from Arabidopsis thaliana),

and Doa (from Drosophila melanogaster). Family members share a highly conserved motif in a subdomain, EHLAMMERILGPLP, of the

kinase domain. This motif is not conserved among kinases in general and may be involved in directing substrate specificity. LAMMER

kinases are thought to play important roles in the control of cellular growth and differentiation. In particular, Clk has been shown to

phosphorylate members of the serine/arginine-rich (SR) family of RNA splicing factors, suggesting that it may play a role in RNA processing.

G313-1 recognizes Clk1. Full-length Clk1 migrates at a reduced molecular weight of ~57 kDa. A full-length Clk1-fusion protein was used as

immunogen.

注意事项：

1.Since applications vary, each investigator should titrate the reagent to obtain optimal results.

2.Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before

discarding to avoid accumulation of potentially explosive deposits in plumbing.

3.Store undiluted at 4°C.